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Pneumothorax

Anesthesia Implications

Updated On: July 23, 2026

Anesthesia Implications

Positive pressure is dangerous - Mechanical ventilation can rapidly enlarge an existing pneumothorax and precipitate tension physiology; a significant untreated pneumothorax should be drained before positive-pressure ventilation.

Avoid nitrous oxide - N2O diffuses into and expands closed air spaces, enlarging a pneumothorax fast — avoid it.

Recognize tension - Sudden hypoxemia, rising airway pressures, hypotension, distended neck veins, absent breath sounds, and tracheal deviation — decompress immediately (needle, then chest tube).

At-risk patients - Trauma, central line placement, barotrauma, bullous lung disease, and recent thoracic procedures raise suspicion; watch after any of these.

Chest tube management - Confirm the drain is working, watch for recurrence, and never clamp a bubbling tube in a ventilated patient.

Pathophysiology

A pneumothorax is air in the pleural space that collapses the lung and impairs ventilation. A tension pneumothorax — air accumulating under pressure — shifts the mediastinum, obstructs venous return, and causes cardiovascular collapse: a true emergency.

Under anesthesia the danger is amplified, because positive-pressure ventilation and nitrous oxide can rapidly enlarge a pneumothorax and convert a simple one into a tension pneumothorax. A high index of suspicion is essential.


Suggested Reading

Onyancha S, Amirmiran B, Dieball T, et al. Suprascapular Chest Tube Placement for Symptomatic Spontaneous Pneumothorax: The Forgotten Access Point. Respirol Case Rep. 2026. PMID: 42466434.
Sharma V, Jose N, Mohan M, et al. Post-operative Desaturation in Prone Spine Surgery; Diagnostic Dilemma in Pneumothorax Due to Barotrauma: A Case Report. J Orthop Case Rep. 2026. PMID: 42428354.
Taskeen F, Singh M, B Y, et al. Post-extubation pneumothorax following bougie-assisted endotracheal tube exchange. BMJ Case Rep. 2026. PMID: 42398983.
Hemmings HC Jr, Yao FF, Goldstein PA, et al, eds. Yao & Artusio's Anesthesiology: Problem-Oriented Patient Management. 10th ed. Wolters Kluwer; 2025.
Gropper MA, Eriksson LI, Fleisher LA, et al, eds. Miller's Anesthesia. 10th ed. Elsevier; 2024.
Hines RL, ed. Stoelting's Anesthesia and Co-Existing Disease. 8th ed. Elsevier; 2021.